Cancer management in humans and animals includes chemoprevention, interception, and many types of treatments. LIU investigators study molecular markers of cancer and evaluate natural products alone and in combination with approved drugs for targeted therapies. The Lewyt College of Veterinary Medicine faculty works on the pharmacology of hormone-dependent cancers to discover new anticancer agents that curb cancer progression and metastases in humans and animals. Please see the website for Dr. Anait S. Levenson for more details on current and future work in this area.
Research in the Pathology and Molecular Pathophysiology focus area addresses national needs in the areas of therapeutics, and basic research into mechanisms of disease that have broad One Health applications. The array of diseases and mechanisms of disease being investigated include work on signal transduction in the pathophysiology associated with airway remodeling in chronic airway inflammatory diseases, such as asthma; understanding the role of redox proteins in the pathophysiology of ischemic diseases and age-related disorders, particularly renal ischemia and reperfusion injury, and age-related macular degeneration (Dr. Jose Godoy). In the field of orthopedics (Dr. Meir Barak) studies bone structure-function relationships, bone material properties, bone modeling and remodeling, and the effects of aging on osteoporosis and bone health.
The program in Molecular Immunology at the Lewyt College of Veterinary Medicine is focused on mechanisms of immune regulation in tissue repair due to autoimmune diseases (such as multiple sclerosis and inflammatory bowel disease), skeletal disorders (such as bone injury), discovering, translating and applying regulatory T (Treg) and stem cells in therapy to restore the normal function of damaged organs and tissues, and airway inflammation and immune responses to diseases such as asthma. The Lewyt College of Veterinary Medicine's molecular immunology research cluster include faculty members Drs. Rodolfo Nino- Fong and Xiaolei Tang. Details of the research being done by these investigators are available on their websites.